BEGIN:VCALENDAR VERSION:2.0 METHOD:PUBLISH PRODID:-//Missouri State University/Calendar of Events//EN CALSCALE:GREGORIAN X-WR-TIMEZONE:America/Chicago BEGIN:VTIMEZONE TZID:America/Chicago BEGIN:DAYLIGHT TZOFFSETFROM:-0600 TZOFFSETTO:-0500 DTSTART:20070311T020000 RRULE:FREQ=YEARLY;BYMONTH=3;BYDAY=2SU TZNAME:CDT END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0500 TZOFFSETTO:-0600 DTSTART:20071104T020000 RRULE:FREQ=YEARLY;BYMONTH=11;BYDAY=1SU TZNAME:CST END:STANDARD END:VTIMEZONE BEGIN:VEVENT UID:5a3e799d-b4a0-4f7e-ac0a-c4a767cfebfe.220111@calendar.missouristate.edu CREATED:20220214T144212Z LAST-MODIFIED:20220214T144212Z LOCATION:Meyer Library\, Duane G. 101 SUMMARY:Chemistry & Biochemistry Seminar: "Biomimetic Macromolecular Nanop latforms: Novel Biochemical Approaches for Rapidly Emerging Viruses" DESCRIPTION:Presenter: Prof. Santimukul Santra (Department of Chemistry\, Pittsburg State University)\n\n\nAs COVID-19 continues to be an ongoing p andemic\, our lab focused to help the society by adopting unique engineer ing concepts and technologies for infectious diseases. Some of these incl ude (i) applying high throughput\, bioinspired nanoplatforms for tracking viral entry and fusion\, (ii) chemical approaches to create novel cataly tic labels for assesment of protective immunity in response to natural in fection and vaccination\, and (iii) designing tunable polymeric formulati ons with diverse functionality for vaccine delivery and management.\n\n\n This presentation will introduce magnetic relaxation as a new bioanalytic al tool to study membrane fusion interactions for enveloped viruses in re al-time for screening antiviral therapeutics. Class I viral fusion protei ns with specific examples of influenza and SARS-CoV-2 that employ diverse fusion triggering mechanisms including low pH\, protease activation\, re ceptor binding or a combination of these will be discussed. On the other hand\, point-of-care test for assessing COVID-19 vaccine immunity will be included. Recent results on unique catalytic labels and its’ integration in lateral flow assay (LFA) technology that allows visualization of test results with naked eye will be highlighted in this presentation. Finally \, a quick look at our smart design for dendritic biomaterials and respon sive nanoplatforms for delivery\, with an ultimate goal of creating effic ient vaccine formulations. Such vaccine delivery platforms\, offering uni que features of carrying large payloads and importantly\, protecting mRNA \, nuclei acids deliverables from nucleases. X-ALT-DESC;FMTTYPE=text/html:<html><head><title></title></head><body><p><s pan>Presenter:&nbsp\;</span>Prof. Santimukul Santra (Department of Chemis try\, Pittsburg State University)</p>\n<p>As COVID-19 continues to be an ongoing pandemic\, our lab focused to help the society by adopting unique engineering concepts and technologies for infectious diseases. Some of t hese include (i) applying high throughput\, bioinspired nanoplatforms for tracking viral entry and fusion\, (ii) chemical approaches to create nov el catalytic labels for assesment of protective immunity in response to n atural infection and vaccination\, and (iii) designing tunable polymeric formulations with diverse functionality for vaccine delivery and manageme nt.</p>\n<p>This presentation will introduce magnetic relaxation as a new bioanalytical tool to study membrane fusion interactions for enveloped v iruses in real-time for screening antiviral therapeutics. Class I viral f usion proteins with specific examples of influenza and SARS-CoV-2 that em ploy diverse fusion triggering mechanisms including low pH\, protease act ivation\, receptor binding or a combination of these will be discussed. O n the other hand\, point-of-care test for assessing COVID-19 vaccine immu nity will be included. Recent results on unique catalytic labels and its’ integration in lateral flow assay (LFA) technology that allows visualiza tion of test results with naked eye will be highlighted in this presentat ion. Finally\, a quick look at our smart design for dendritic biomaterial s and responsive nanoplatforms for delivery\, with an ultimate goal of cr eating efficient vaccine formulations. Such vaccine delivery platforms\, offering unique features of carrying large payloads and importantly\, pro tecting mRNA\, nuclei acids deliverables from nucleases.</p>\n<p></p></bo dy></html> DTSTART;TZID=America/Chicago:20220216T153500 DTEND;TZID=America/Chicago:20220216T162500 SEQUENCE:0 URL: CATEGORIES:Public,Alumni,Current Students,Faculty,Future Students,Staff END:VEVENT END:VCALENDAR