BEGIN:VCALENDAR VERSION:2.0 METHOD:PUBLISH PRODID:-//Missouri State University/Calendar of Events//EN CALSCALE:GREGORIAN X-WR-TIMEZONE:America/Chicago BEGIN:VTIMEZONE TZID:America/Chicago BEGIN:DAYLIGHT TZOFFSETFROM:-0600 TZOFFSETTO:-0500 DTSTART:20070311T020000 RRULE:FREQ=YEARLY;BYMONTH=3;BYDAY=2SU TZNAME:CDT END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0500 TZOFFSETTO:-0600 DTSTART:20071104T020000 RRULE:FREQ=YEARLY;BYMONTH=11;BYDAY=1SU TZNAME:CST END:STANDARD END:VTIMEZONE BEGIN:VEVENT UID:3c291aa6-bc05-4510-b17c-6fcc83c43497.222140@calendar.missouristate.edu CREATED:20220906T203104Z LAST-MODIFIED:20220906T203104Z LOCATION:Roy Blunt Hall 003 SUMMARY:Biology Seminar: Chemistry Orchestrates with Biology in the Age of Cancer and Infectious Diseases DESCRIPTION:Speaker: Dr. Santimukul Santra\n\n\nAssociate Professor\, Depa rtment of Chemistry\, Pittsburg State University\n\n\nDuring COVID-19\, D r. Santra's lab focused on helping society by adopting unique engineering concepts and nanotechnologies for infectious diseases. Some of these inc lude applying high throughput\, bioinspired nanoplatforms for tracking vi ral entry and fusion\; chemical approaches to create novel catalytic labe ls for assessment of protective immunity in response to natural infection and vaccination\; and designing tunable polymeric formulations for cance r drug delivery\, and SARS-CoV-2 vaccine delivery and management.\n\n\nTh is presentation will introduce magnetic relaxation as a new bioanalytical tool to study membrane fusion interactions for enveloped viruses in real -time for screening antiviral therapeutics. Class I viral fusion proteins with specific examples of influenza and SARS-CoV-2 that employ diverse f usion triggering mechanisms including low pH\, protease activation\, rece ptor binding\, or a combination of these will be discussed. On the other hand\, a point-of-care test for assessing COVID-19 vaccine immunity will be included. Recent results on unique catalytic labels and its’ integrati on in lateral flow assay (LFA) technology that allows visualization of te st results with the naked eye will be highlighted in this presentation. F inally\, a quick look at their smart design for dendritic biomaterials an d responsive nanoplatforms for targeted drug delivery for cancer therapy\ , which is also used for creating efficient SARS-CoV-2 vaccine formulatio ns. Such vaccine delivery platforms offer unique features of carrying lar ge payloads and importantly\, protecting mRNA\, and nuclei acids delivera bles from nucleases. X-ALT-DESC;FMTTYPE=text/html:<html><head><title></title></head><body><p>Sp eaker: Dr. Santimukul Santra</p>\n<p>Associate Professor\, Department of Chemistry\, Pittsburg State University</p>\n<p>During COVID-19\, Dr. Sant ra's lab focused&nbsp\;on helping society by adopting unique engineering concepts and nanotechnologies for infectious diseases. Some of these incl ude applying high throughput\, bioinspired nanoplatforms for tracking vir al entry and fusion\; chemical approaches to create novel catalytic label s for assessment of protective immunity in response to natural infection and vaccination\; and designing tunable polymeric formulations for cancer drug delivery\, and SARS-CoV-2 vaccine delivery and management.</p>\n<p> This presentation will introduce magnetic relaxation as a new bioanalytic al tool to study membrane fusion interactions for enveloped viruses in re al-time for screening antiviral therapeutics. Class I viral fusion protei ns with specific examples of influenza and SARS-CoV-2 that employ diverse fusion triggering mechanisms including low pH\, protease activation\, re ceptor binding\, or a combination of these will be discussed. On the othe r hand\, a point-of-care test for assessing COVID-19 vaccine immunity wil l be included. Recent results on unique catalytic labels and its’ integra tion in lateral flow assay (LFA) technology that allows visualization of test results with the naked eye will be highlighted in this presentation. Finally\, a quick look at their smart design for dendritic biomaterials and responsive nanoplatforms for targeted drug delivery for cancer therap y\, which is also used for creating efficient SARS-CoV-2 vaccine formulat ions. Such vaccine delivery platforms offer unique features of carrying l arge payloads and importantly\, protecting mRNA\, and nuclei acids delive rables from nucleases.</p></body></html> DTSTART;TZID=America/Chicago:20220916T160000 DTEND;TZID=America/Chicago:20220916T170000 SEQUENCE:0 URL:https://biology.missouristate.edu/ CATEGORIES:Public,Alumni,Current Students,Faculty,Future Students,Staff END:VEVENT END:VCALENDAR