BEGIN:VCALENDAR VERSION:2.0 METHOD:PUBLISH PRODID:-//Missouri State University/Calendar of Events//EN CALSCALE:GREGORIAN X-WR-TIMEZONE:America/Chicago BEGIN:VTIMEZONE TZID:America/Chicago BEGIN:DAYLIGHT TZOFFSETFROM:-0600 TZOFFSETTO:-0500 DTSTART:20070311T020000 RRULE:FREQ=YEARLY;BYMONTH=3;BYDAY=2SU TZNAME:CDT END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:-0500 TZOFFSETTO:-0600 DTSTART:20071104T020000 RRULE:FREQ=YEARLY;BYMONTH=11;BYDAY=1SU TZNAME:CST END:STANDARD END:VTIMEZONE BEGIN:VEVENT UID:f7bbf016-fb04-464f-bc0c-7a5db5506d10.222875@calendar.missouristate.edu CREATED:20221121T143955Z LAST-MODIFIED:20221121T143955Z LOCATION:Kemper Hall 204 SUMMARY:PAMS Seminar: "Multiple Attractor in tumor immune dynamics" by Dr. Ruma Dutta DESCRIPTION:Dr. Ruma DuttaPAMSMissouri State University\n\n\nAbstract:Rece nt progress in cancer immunology and advances in immunotherapy suggest th at our immune system plays a fundamental role in combating tumor. So\, it is necessary to understand complex dynamics of the tumor-immune system. The multi-dimensional nature of tumor-immune interactions requires cross- disciplinary approaches to capture more realistic dynamics of essential b iology. The growth of a cancerous cell in vivo cancer cells are host cell s that begin to proliferate in an uncontrolled and non-specific way that leads to development of tumor. Mathematical models of tumor-immune dynami cs have added to our understanding of how host immune cell and cancer cel l evolve and interact. Mathematical models of tumor-immune interactions p rovide an analytical framework in which to address specific questions reg arding tumor-immune dynamics. Recent experimental studies have brought to light new information about how the immune system of the mouse responds to the presence of tumor. Tumor cells are modified to express higher leve ls of immune stimulating NKG2D ligands. Additionally\, ligand transduced tumor cells stimulate protective immunity to tumor challenge. Based on th eir experimental studies\, groups have developed mathematical model for t umor-immune dynamics interactions which focus on the role of Natural kill er (NK) and CD8+T cells in tumor surveillance. The model was based on man y clinical and oncology data. X-ALT-DESC;FMTTYPE=text/html:<html><head><title></title></head><body><p><b >Dr.&nbsp\;Ruma Dutta</b><br><b>PAMS</b><br><b>Missouri State University< /b></p>\n<p>Abstract:<br>Recent progress in cancer immunology and advance s in immunotherapy suggest that our immune system plays a fundamental rol e in combating tumor. So\, it is necessary to understand complex dynamics of the tumor-immune system. The multi-dimensional nature of tumor-immune interactions requires cross-disciplinary approaches to capture more real istic dynamics of essential biology. The growth of a cancerous cell in vi vo cancer cells are host cells that begin to proliferate in an uncontroll ed and non-specific way that leads to development of tumor. Mathematical models of tumor-immune dynamics have added to our understanding of how ho st immune cell and cancer cell evolve and interact. Mathematical models o f tumor-immune interactions provide an analytical framework in which to a ddress specific questions regarding tumor-immune dynamics. Recent experim ental studies have brought to light new information about how the immune system of the mouse responds to the presence of tumor. Tumor cells are mo dified to express higher levels of immune stimulating NKG2D ligands. Addi tionally\, ligand transduced tumor cells stimulate protective immunity to tumor challenge. Based on their experimental studies\, groups have devel oped mathematical model for tumor-immune dynamics interactions which focu s on the role of Natural killer (NK) and CD8+T cells in tumor surveillanc e. The model was based on many clinical and oncology data.</p></body></ht ml> DTSTART;TZID=America/Chicago:20221201T160000 DTEND;TZID=America/Chicago:20221201T170000 SEQUENCE:0 URL:https://physics.missouristate.edu/seminars.htm CATEGORIES:Public,Alumni,Current Students,Faculty,Future Students,Staff END:VEVENT END:VCALENDAR